High affinity is insufficient for strong B cell activation by HIV broadly neutralising antibodies
Abstract HIV broadly neutralizing antibodies (bnAbs) have been widely studied, and inducing a robust broadly neutralizing response remains a goal for many human vaccine studies. Much research focusses on creating higher affinity antigens to target bnAb precursors, however this ignores the role of no...
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| Автори: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2026-05-01
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| Серія: | npj Vaccines |
| Онлайн доступ: | https://doi.org/10.1038/s41541-026-01468-y |
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