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Retinoic acid restores adult hippocampal neurogenesis and reverses spatial memory deficit in vitamin A deprived rats.

A dysfunction of retinoid hippocampal signaling pathway has been involved in the appearance of affective and cognitive disorders. However, the underlying neurobiological mechanisms remain unknown. Hippocampal granule neurons are generated throughout life and are involved in emotion and memory. Here,...

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Principais autores: Emilie Bonnet, Katia Touyarot, Serge Alfos, Véronique Pallet, Paul Higueret, Djoher Nora Abrous
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC2567033?pdf=render
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