Retinoic acid normalizes nuclear receptor mediated hypo-expression of proteins involved in β-amyloid deposits in the cerebral cortex of vitamin A deprived rats

Recent data have revealed that disruption of vitamin A signaling observed in Alzheimer's disease (AD) leads to a deposition of β-amyloid (Aβ). The aim of this study was to precise the role of vitamin A and its nuclear receptors (RAR) in the processes leading to the Aβ deposits. Thus, the effect of v...

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Bibliografiske detaljer

Principais autores:	Marianne Husson, Valérie Enderlin, André Delacourte, Nadirah Ghenimi, Serge Alfos, Véronique Pallet, Paul Higueret
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2006-07-01
Serier:	Neurobiology of Disease
Fag:	Vitamin A deficiency Retinoic acid nuclear receptor (RAR) Amyloid precursor protein (APP) β-Site APP-cleaving enzyme (BACE) APP carboxy-terminal fragment (CTF) Rat cerebral cortex
Online adgang:	http://www.sciencedirect.com/science/article/pii/S0969996106000143
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