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Natural xanthones as α-Mangostin induce vasorelaxation involving key gating residues in the S6 domain of BK channels

Polyphenolic compounds are widely explored for health benefits, including hypertension, but their active ingredients, molecular targets, and mechanisms remain poorly defined. We identify the xanthone Mangostin from Garcinia mangostana as a potent modulator of several potassium channels, with large-c...

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שמור ב:
מידע ביבליוגרפי
Principais autores: Soenke Cordeiro, Robert Patejdl, Thomas Baukrowitz, Marianne A Musinszki
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications Ltd 2026-05-01
סדרה:eLife
נושאים:
גישה מקוונת:https://elifesciences.org/articles/109479
תגים: הוספת תג
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