Vaccinia virus mRNAs containing long 5′-poly(A)-leaders lack a canonical 5′-methylguanosine cap
Abstract The vaccinia virus (VACV) is a prototypical poxvirus that was originally used to eradicate smallpox. Half a century ago, investigation into VACV mRNA substantially contributed to the fundamental discovery of the 5′ mRNA cap, a hallmark of all eukaryotic and many viral mRNAs. VACV research a...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Portfolio
2025-12-01
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| Серии: | Nature Communications |
| Online-ссылка: | https://doi.org/10.1038/s41467-025-67916-w |
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