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Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E

Abstract Background Pancreatic cancer is one of the most malignant cancers. The overall 5-year survival rate of its patients is 8%, the lowest among major cancer types. It is very urgent to study the development mechanisms of this cancer and provide potential targets for therapeutics design. Glucose...

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Hlavní autoři: Xuhui Ma, Boya Li, Jie Liu, Yan Fu, Yongzhang Luo
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2019-02-01
Edice:Journal of Experimental & Clinical Cancer Research
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On-line přístup:http://link.springer.com/article/10.1186/s13046-019-1053-y
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