DeBouganin Diabody Fusion Protein Overcomes Drug Resistance to ADCs Comprised of Anti-Microtubule Agents

Antibody drug conjugates (ADC), comprised of highly potent small molecule payloads chemically conjugated to a full-length antibody, represent a growing class of therapeutic agents. The targeting of cytotoxic payloads via the specificity and selectivity of the antibody has led to substantial clinical...

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Hlavní autoři:	Shilpa Chooniedass, Rachelle L. Dillon, Arjune Premsukh, Peter J. Hudson, Gregory P. Adams, Glen C. MacDonald, Jeannick Cizeau
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2016-12-01
Edice:	Molecules
Témata:	immunotoxin deBouganin ribosome inactivating protein HER2 C6.5 diabody
On-line přístup:	http://www.mdpi.com/1420-3049/21/12/1741
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