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CNOT11 depletion is associated with autophagy-related responses and IL-6–JAK–STAT signaling in cancer cells

IntroductionThe CCR4‐NOT complex is a central regulator of deadenylation-mediated mRNA decay, yet the role of its vertebrate-specific subunit CNOT11 remains unclear.MethodsWe investigated the role of CNOT11 in cellular stress responses using siRNA-mediated knockdown, immunoblotting, immunoprecipitat...

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Huvudupphov: Saori Nishijima, Toru Suzuki, Tadashi Yamamoto
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2026-07-01
Serie:Frontiers in Cell and Developmental Biology
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Länkar:https://www.frontiersin.org/articles/10.3389/fcell.2026.1854333/full
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