Axonal membrane stretch suppresses neuronal excitability by activating mechanosensitive K2P channels at the node of Ranvier

Abstract Saltatory conduction is the propagation of action potentials along myelinated nerves, which enables fast propagation through the node of Ranvier. Recently, we demonstrated that K2P channels, TWIK-related K+ channel-1 (TREK-1), and TWIK-related arachidonic acid-activated K + channel (TRAAK),...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Hirosato Kanda, Koichi Noguchi, Yi Dai
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2023-01-01
Цуврал:	Molecular Brain
Нөхцлүүд:	Node of Ranvier Two-pore-domain potassium channels Membrane stretch Action potential Single-channel activity
Онлайн хандалт:	https://doi.org/10.1186/s13041-023-01000-6
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!