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EGCG activates Keap1/P62/Nrf2 pathway, inhibits iron deposition and apoptosis in rats with cerebral hemorrhage

Abstract Intracerebral hemorrhage (ICH) is a common cerebrovascular disease characterized by a high incidence, disability rate, and mortality. Epigallocatechin gallate (EGCG), a key catechin compound found in green tea, has received increasing attention for its potential neuroprotective and therapeu...

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Hlavní autoři: Liang Hao, Aobo Zhang, Dongsheng Lv, LuLu Cong, Zhimin Sun, Liqiang Liu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-12-01
Edice:Scientific Reports
Témata:
EGCG
Intracerebral hemorrhage
Ferroptosis
Oxidative stress
Cell apoptosis
On-line přístup:https://doi.org/10.1038/s41598-024-82938-y
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