Inflammation and platelet hyperresponsiveness in coronary artery disease and the influence of Talin-1/αIIbβ3-mediated bidirectional signaling pathway

BackgroundWhile platelet hyperreactivity constitutes an independent risk factor for major adverse cardiovascular events (MACEs) in coronary artery disease, its molecular underpinnings remain poorly characterized. Recent advances in transcriptomic profiling have revealed potential associations with s...

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Автори:	Shengnan Shi, Jiaming Gao, Yehao Zhang, Min Zhan, Zhanfei Tan, Peili Wang, Jianhua Fu, Jianxun Liu
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2025-03-01
Серія:	Frontiers in Pharmacology
Предмети:	coronary heart disease platelet hyperreactivity Talin-1 and αIIbβ3-mediated bidirectional signaling pathway platelet transcriptome interleukin
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1535182/full
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