Inflammation and platelet hyperresponsiveness in coronary artery disease and the influence of Talin-1/αIIbβ3-mediated bidirectional signaling pathway

BackgroundWhile platelet hyperreactivity constitutes an independent risk factor for major adverse cardiovascular events (MACEs) in coronary artery disease, its molecular underpinnings remain poorly characterized. Recent advances in transcriptomic profiling have revealed potential associations with s...

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Príomhchruthaitheoirí:	Shengnan Shi, Jiaming Gao, Yehao Zhang, Min Zhan, Zhanfei Tan, Peili Wang, Jianhua Fu, Jianxun Liu
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2025-03-01
Sraith:	Frontiers in Pharmacology
Ábhair:	coronary heart disease platelet hyperreactivity Talin-1 and αIIbβ3-mediated bidirectional signaling pathway platelet transcriptome interleukin
Rochtain ar líne:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1535182/full
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