SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis

ABSTRACT Lung cancer remains a leading cause for global cancer‐related mortality, with therapeutic resistance and metastasis posing major clinical challenges. The special AT‐rich sequence‐binding protein 2 (SATB2) is a well‐established tumor suppressor in NSCLC, but its downstream epigenetic and met...

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Auteurs principaux:	Ting Wen, Lihua Yang, Shuang Cai, Yunxia Liu, Jianan Fan, Peng Wu, Beibei Gao, Xiaoge Xie, Hong Sun, Sida Qin, Qiao Yi Chen
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2026-04-01
Collection:	Advanced Science
Sujets:	H3K9 delactylation HDAC3 LCN2 lung cancer SATB2
Accès en ligne:	https://doi.org/10.1002/advs.202522996
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