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METTL14 suppresses the expression of YAP1 and the stemness of triple-negative breast cancer

Abstract Background Triple-negative breast cancer (TNBC) has pronounced stemness that is associated with relapse. N6-methyladenosine (m6A) plays a crucial role in shaping cellular behavior by modulating transcript expression. However, the role of m6A in TNBC stemness, as well as the mechanisms gover...

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Principais autores: Xupeng Bai, Jiarui Liu, Shujie Zhou, Lingzhi Wu, Xiaojie Feng, Pumin Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-11-01
coleção:Journal of Experimental & Clinical Cancer Research
Assuntos:
TNBC
Stemness
METTL14
m6A
YAP1
LSD1
Acesso em linha:https://doi.org/10.1186/s13046-024-03225-2
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