Molecular insights into the regulation of GNPTαβ by LYSET
Abstract In vertebrates, newly synthesized lysosomal enzymes traffic to lysosomes through the mannose-6-phosphate (M6P) pathway. The Golgi membrane protein LYSET was recently discovered to regulate lysosome biogenesis by controlling the level of GlcNAc-1-phosphotransferase (GNPT). However, its worki...
Na minha lista:
| Principais autores: | , , , , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2026-03-01
|
| Colecção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-026-70402-6 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|