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Mechanistic within-host mathematical model of inhalational anthrax.

We present a mathematical model of the dynamics of Bacillus anthracis bacteria within the lymph nodes and blood of a host, following inhalation of an initial dose of spores. We also incorporate the dynamics of protective antigen, which is the binding component of the anthrax toxin produced by the ba...

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Autores principales: Bevelynn Whaler, Grant Lythe, Joseph J Gillard, Thomas R Laws, Jonathan Carruthers, Thomas Finnie, Carmen Molina-París, Martín López-García
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2025-09-01
Colección:PLoS Computational Biology
Acceso en línea:https://doi.org/10.1371/journal.pcbi.1013439
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