Chromosomal domain formation by archaeal SMC, a roadblock protein, and DNA structure

Abstract In eukaryotes, structural maintenance of chromosomes (SMC) complexes form topologically associating domains (TADs) by extruding DNA loops and being stalled by roadblock proteins. It remains unclear whether a similar mechanism of domain formation exists in prokaryotes. Using high-resolution...

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Autors principals:	Kodai Yamaura, Naomichi Takemata, Masashi Kariya, Ayami Osaka, Sonoko Ishino, Masataka Yamauchi, Tomonori Tamura, Itaru Hamachi, Shoji Takada, Yoshizumi Ishino, Haruyuki Atomi
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-02-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-025-56197-y
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