Metal- and Semimetal-Containing Inhibitors of Thioredoxin Reductase as Anticancer Agents
The mammalian thioredoxin reductases (TrxRs) are a family of selenium-containing pyridine nucleotide disulfide oxidoreductases playing a central role in cellular redox homeostasis and signaling pathways. Recently, these selenoproteins have emerged as promising therapeutic targets for anticancer drug...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI AG
2015-07-01
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| Serie: | Molecules |
| Soggetti: | |
| Accesso online: | http://www.mdpi.com/1420-3049/20/7/12732 |
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