Negatively charged phospholipids doped liposome delivery system for mRNA with high transfection efficiency and low cytotoxicity

Messenger RNA (mRNA) has become one of the most potential drugs in recent years. However, efficient and safe delivery of fragile and easily degradable mRNA is a major challenge. Appropriate delivery system (DS) determines the final effect of mRNA. Cationic lipids play a crucial and decisive role in...

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Autores principales:	Lin Wang, Huanchun Xing, Shuai Guo, Wenbin Cao, Zinan Zhang, Lijuan Huang, Sui Xin, Yuan Luo, Yongan Wang, Jun Yang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis Group 2023-12-01
Colección:	Drug Delivery
Materias:	Liposome mRNA transfection nanocarrier lipid nanoparticle mRNA drug
Acceso en línea:	https://www.tandfonline.com/doi/10.1080/10717544.2023.2219869
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