An Efficient and Footprint-Free Protocol for the Transdifferentiation of Hepatocytes Into Insulin-Producing Cells With IVT mRNAs
BackgroundDirect transdifferentiation of adult somatic cells into insulin-producing cells (IPCs) is a promising approach for cell-based therapies for type 1 diabetes mellitus. Liver cells are an ideal source for generating IPCs because they have regenerative ability and a developmental process simil...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2020-06-01
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| Seria: | Frontiers in Genetics |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.frontiersin.org/article/10.3389/fgene.2020.00575/full |
| Etykiety: |
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