Proteome-wide mendelian randomization reveals circulating proteins causally associated with childhood body mass index

Abstract Childhood obesity is a major public health problem, affecting one in 5 youths. We aimed to characterize biomarkers for pediatric obesity among circulating proteins using Mendelian randomization (MR). We utilized genome-wide significant cis-protein quantitative trait loci (pQTL) from three l...

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Detalhes bibliográficos

Principais autores:	Raphael Avocegamou, Basile Jumentier, Kaossarath Fagbemi, Nahid Yazdanpanah, Mojgan Yazdanpanah, Isabel Gamache, Despoina Manousaki
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-12-01
coleção:	Scientific Reports
Assuntos:	Proteins Pediatric obesity Mendelian randomization Causal inference
Acesso em linha:	https://doi.org/10.1038/s41598-025-31836-y
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