Age at menarche, age at natural menopause, and risk of rheumatoid arthritis — a Mendelian randomization study

Abstract Background Hormonal reproductive factors have been suggested to play an important role in the etiology of rheumatoid arthritis (RA), an autoimmune inflammatory disorder affecting primarily women. We conducted a two-sample Mendelian randomization (MR) study examining three relevant exposures...

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Detalhes bibliográficos

Principais autores:	Jingjing Zhu, Zheng Niu, Lars Alfredsson, Lars Klareskog, Leonid Padyukov, Xia Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-04-01
coleção:	Arthritis Research & Therapy
Assuntos:	Mendelian randomization Rheumatoid arthritis Age at menarche Age at natural menopause Age at first birth
Acesso em linha:	https://doi.org/10.1186/s13075-021-02495-x
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