Internal regulation between constitutively expressed T cell co-inhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants

Immunologic self-tolerance involves signals from co-inhibitory receptors. Several T cell co-inhibitors, including PD-1, are expressed upon activation, whereas CD5 and BTLA are expressed constitutively. The relationship between constitutively expressed co-inhibitors and when they are needed is unknow...

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Autori principali:	Adeolu O. Adegoke, Govindarajan Thangavelu, Ting-Fang Chou, Marcos I. Petersen, Kiyokazu Kakugawa, Julia F. May, Kevin Joannou, Qingyang Wang, Kristofor K. Ellestad, Louis Boon, Peter A. Bretscher, Hilde Cheroutre, Mitchell Kronenberg, Troy A. Baldwin, Colin C. Anderson
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	The Royal Society 2024-10-01
Serie:	Open Biology
Soggetti:	T cells autoimmunity BTLA CD5 recent thymic emigrants tolerance
Accesso online:	https://royalsocietypublishing.org/doi/10.1098/rsob.240178
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