Internal regulation between constitutively expressed T cell co-inhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants

Immunologic self-tolerance involves signals from co-inhibitory receptors. Several T cell co-inhibitors, including PD-1, are expressed upon activation, whereas CD5 and BTLA are expressed constitutively. The relationship between constitutively expressed co-inhibitors and when they are needed is unknow...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Adeolu O. Adegoke, Govindarajan Thangavelu, Ting-Fang Chou, Marcos I. Petersen, Kiyokazu Kakugawa, Julia F. May, Kevin Joannou, Qingyang Wang, Kristofor K. Ellestad, Louis Boon, Peter A. Bretscher, Hilde Cheroutre, Mitchell Kronenberg, Troy A. Baldwin, Colin C. Anderson
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	The Royal Society 2024-10-01
Цуврал:	Open Biology
Нөхцлүүд:	T cells autoimmunity BTLA CD5 recent thymic emigrants tolerance
Онлайн хандалт:	https://royalsocietypublishing.org/doi/10.1098/rsob.240178
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!