Dendrogenin A and B two new steroidal alkaloides increasing neural responsiveness in deafened guinea pig

Aim: To investigate the therapeutic potential for treating inner ear damage of two new steroidal alkaloid compounds, Dendrogenin A and Dendrogenin B, previously shown to be potent inductors of cell differentiation. Methods: Guinea pigs, unilaterally deafened by neomycin infusion, received a cochlea...

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Autores principales:	Anette Elisabeth Fransson, Philippe eDe Medina, Michael ePaillasse, Sandrine eSilvente-Poirot, Marc ePoirot, Mats eUlfendahl
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2015-07-01
Colección:	Frontiers in Aging Neuroscience
Materias:	cochlear implant auditory nerve steroidal alkaloid spiral ganglion neuron electrically-evoked auditory brainstem response
Acceso en línea:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00145/full
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