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Immunogenic cell death and bystander killing: expanding the therapeutic potential of modern antibody-drug conjugates

HER3-DXd and T-DXd are antibody-drug conjugates (ADCs) that induce immunogenic cell death and bystander killing, enhancing antitumor immunity beyond target-specific cytotoxicity. These findings highlight novel mechanisms that can overcome antigen heterogeneity and suggest opportunities for improving...

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Detaylı Bibliyografya
Asıl Yazarlar: Oliver Kepp, Guido Kroemer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2025-12-01
Seri Bilgileri:OncoImmunology
Konular:
Online Erişim:https://www.tandfonline.com/doi/10.1080/2162402X.2025.2533488
Etiketler: Etiketle
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