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The Dynamics of Somatic Mutagenesis During Life in Humans

From conception to death, human cells accumulate somatic mutations in their genomes. These mutations can contribute to the development of cancer and non-malignant diseases and have also been associated with aging. Rapid technological developments in sequencing approaches in the last few years and th...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Freek Manders, Ruben van Boxtel, Sjors Middelkamp
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-12-01
Schriftenreihe:Frontiers in Aging
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fragi.2021.802407/full
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