Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy
Abstract Background Myopathy and exercise intolerance are prominent clinical features in carriers of a point-mutation or large-scale deletion in the mitochondrial DNA (mtDNA). In the majority of patients, the mtDNA mutation is heteroplasmic with varying mutation loads between tissues of an individua...
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| Автори: | , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2019-12-01
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| Серія: | Stem Cell Research & Therapy |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s13287-019-1510-8 |
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