Prevention of Postprandial Hyperglycemia by Ophthalmic Nanoparticles Based on Protamine Zinc Insulin in the Rabbit

Postprandial hyperglycemia, a so-called blood glucose spike, is associated with enhanced risks of diabetes mellitus (DM) and its complications. In this study, we attempted to design nanoparticles (NPs) of protamine zinc insulin (PZI) by the bead mill method, and prepare ophthalmic formulations based...

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Bibliografische gegevens

Hoofdauteurs:	Saori Deguchi, Fumihiko Ogata, Takumi Isaka, Hiroko Otake, Yosuke Nakazawa, Naohito Kawasaki, Noriaki Nagai
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2021-03-01
Reeks:	Pharmaceutics
Onderwerpen:	insulin nanoparticle postprandial hyperglycemia instillation polyacrylic acid
Online toegang:	https://www.mdpi.com/1999-4923/13/3/375
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