A Factor H-Fc fusion protein increases complement-mediated opsonophagocytosis and killing of community associated methicillin-resistant Staphylococcus aureus.

Staphylococcus aureus employs a multitude of immune-evasive tactics to circumvent host defenses including the complement system, a component of innate immunity central to controlling bacterial infections. With antibiotic resistance becoming increasingly common, there is a dire need for novel therapi...

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Principais autores:	Megan A G Sage, Katelyn D Cranmer, Michele L Semeraro, Shelby Ma, Elena V Galkina, Y Tran, Keith L Wycoff, Julia A Sharp
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2022-01-01
Colecção:	PLoS ONE
Acesso em linha:	https://doi.org/10.1371/journal.pone.0265774
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