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Development of flow cytometric opsonophagocytosis and antibody-mediated complement deposition assays for non-typeable Haemophilus influenzae

Abstract Background Haemophilus influenzae is found in the nasopharynx of 80% of the human population. While colonisation with non-typeable Haemophilus influenzae (NTHi) is usually asymptomatic, it is capable of causing acute and chronic otitis media (OM) in infants, invasive disease in susceptible...

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Principais autores: Stephen R. Thomas, Stephanie Leung, Katy Knox, Tom M. A. Wilkinson, Karl J. Staples, Pascal Lestrate, Dominique Wauters, Andrew Gorringe, Stephen C. Taylor
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-10-01
coleção:BMC Microbiology
Assuntos:
Non-typeable Haemophilus influenzae
Antibody
Opsonophagocytosis
Complement
Flow cytometry
Vaccine
Acesso em linha:http://link.springer.com/article/10.1186/s12866-018-1314-5
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