NNMT promotes the progression of intrahepatic cholangiocarcinoma by regulating aerobic glycolysis via the EGFR-STAT3 axis

Abstract Nicotinamide N-methyltransferase (NNMT), a member of the N-methyltransferase family, plays an important role in tumorigenesis. However, its expression and biological functions in intrahepatic cholangiocarcinoma (iCCA) remain to be established. In our study, we identified NNMT as an oncogene...

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Bibliografische Detailangaben

Hauptverfasser:	Shounan Lu, Shanjia Ke, Chaoqun Wang, Yanan Xu, Zihao Li, Keda Song, Miaoyu Bai, Menghua Zhou, Hongjun Yu, Bing Yin, Xinglong Li, Zhigang Feng, Yongliang Hua, Shangha Pan, Hongchi Jiang, Linqiang Li, Yaohua Wu, Yong Ma
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2022-07-01
Schriftenreihe:	Oncogenesis
Online-Zugang:	https://doi.org/10.1038/s41389-022-00415-5
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