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Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

ABSTRACT Breast cancer metastasis claims the majority of breast cancer‐related deaths. Anoikis resistance is a key prerequisite for CTCs survival and metastasis. Previous studies have demonstrated that Nicotinamide N‐methyltransferase (NNMT) plays a crucial role in cancer metastasis and apoptosis re...

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Principais autores: Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-05-01
Serier:Advanced Science
Fag:
anoikis
breast cancer
CTCs
FAO
NNMT
Online adgang:https://doi.org/10.1002/advs.202522837
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