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Escape from X inactivation varies across genes and tissues and shapes sex-biased sex chromosome gene expression

Abstract Sex differences in human health and disease are shaped by complex interactions between hormones, environment, and genetic factors – including those associated with sex chromosomes. While X chromosome inactivation (XCI) in females generally silences one copy of the X to equalize dosage with...

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Autor principal: Alex R. DeCasien
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-02-01
Colecção:BMC Genomics
Assuntos:
Acesso em linha:https://doi.org/10.1186/s12864-026-12611-3
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