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Escape from X inactivation varies across genes and tissues and shapes sex-biased sex chromosome gene expression

Abstract Sex differences in human health and disease are shaped by complex interactions between hormones, environment, and genetic factors – including those associated with sex chromosomes. While X chromosome inactivation (XCI) in females generally silences one copy of the X to equalize dosage with...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Alex R. DeCasien
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2026-02-01
Cyfres:BMC Genomics
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s12864-026-12611-3
Tagiau: Ychwanegu Tag
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