Myeloid PHD2 Conditional Knockout Improves Intraplaque Angiogenesis and Vascular Remodeling in a Murine Model of Venous Bypass Grafting

Background Intraplaque angiogenesis occurs in response to atherosclerotic plaque hypoxia, which is driven mainly by highly metabolically active macrophages. Improving plaque oxygenation by increasing macrophage hypoxic signaling, thus stimulating intraplaque angiogenesis, could restore cellular func...

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Hlavní autoři:	Thijs J. Sluiter, Renée J. H. A. Tillie, Alwin de Jong, Jenny B. G. de Bruijn, Hendrika A. B. Peters, Remco van de Leijgraaf, Raghed Halawani, Michelle Westmaas, Lineke I. W. Starink, Paul H. A. Quax, Judith C. Sluimer, Margreet R. de Vries
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2024-02-01
Edice:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Témata:	atherosclerosis hypoxia intraplaque angiogenesis intraplaque hemorrhage macrophage vein graft disease
On-line přístup:	https://www.ahajournals.org/doi/10.1161/JAHA.123.033109
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