Genotypic and haplotype analysis of SOCS3 gene polymorphisms (rs4969169, rs12953258, rs1061489) in association with clinicopathological factors in breast cancer

Abstract Background Breast cancer (BC) is the most common malignancy diagnosed among women worldwide. The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway plays a critical role in regulating cellular differentiation, maturation, proliferation, and apoptosis...

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Detalhes bibliográficos

Principais autores:	Raviteja Reddy Alipeddi, Chiranjeevi Padala, Kaushik Puranam, Kayalvili Ulaganathan, Rani Durga Neeharika, Pallavi Sampanmudumby, Sanjeeva kumari Chinta, Surekha Rani Hanumanth
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
Colecção:	BMC Medical Genomics
Assuntos:	Breast cancer PCR-RFLP ARMS-PCR Single nucleotide polymorphisms SOCS3
Acesso em linha:	https://doi.org/10.1186/s12920-025-02284-4
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