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PROTACs in cancer therapy: targeted degradation of GPX4, PARP and epigenetic regulators

The degradation of overexpressed proteins has emerged as a promising strategy for halting disease progression, particularly in cancer. Traditional small-molecule drugs often face limitations in the elimination of pathogenic proteins, leading to the development of targeted protein degradation (TPD) a...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Sunny Periyasamy, Thyla Jarrett, Joe Truong, Rachid Skouta
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis Group 2026-12-01
Rangatū:Journal of Enzyme Inhibition and Medicinal Chemistry
Ngā marau:
Urunga tuihono:https://www.tandfonline.com/doi/10.1080/14756366.2026.2636394
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