Identification of truncated variants in GLI family zinc finger 3 (GLI3) associated with polydactyly

Abstract Background Polydactyly is a prevalent congenital anomaly with an incidence of 2.14 per 1000 live births in China. GLI family zinc finger 3 (GLI3) is a classical causative gene of polydactyly, and serves as a pivotal transcription factor in the hedgehog signaling pathway, regulating the deve...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Run-Yan Wang, Qin Xiong, Si-Hua Chang, Jie-Yuan Jin, Rong Xiang, Lei Zeng, Fang Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-07-01
Colecção:	Journal of Orthopaedic Surgery and Research
Assuntos:	Polydactyly GLI3 Truncated variant Isolated polydactyly Greig cephalopolysyndactyly syndrome
Acesso em linha:	https://doi.org/10.1186/s13018-024-04928-0
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!