Low frequency of mismatch repair deficiency in gallbladder cancer

Abstract Background DNA mismatch repair (MMR) deficiency is a major pathway of genomic instability in cancer. It leads to the accumulation of numerous mutations predominantly at microsatellite sequences, a phenotype known as microsatellite instability (MSI). MSI tumors have a distinct clinical behav...

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Principais autores:	Benjamin Goeppert, Stephanie Roessler, Marcus Renner, Moritz Loeffler, Stephan Singer, Melina Rausch, Thomas Albrecht, Arianeb Mehrabi, Monika Nadja Vogel, Anita Pathil, Elena Czink, Bruno Köhler, Christoph Springfeld, Christian Rupp, Karl Heinz Weiss, Peter Schirmacher, Magnus von Knebel Doeberitz, Matthias Kloor
格式:	Artigo
語言:	Inglês
出版:	BMC 2019-05-01
叢編:	Diagnostic Pathology
主題:	Biliary tract cancer Gallbladder cancer DNA mismatch repair deficiency Microsatellite instability
在線閱讀:	http://link.springer.com/article/10.1186/s13000-019-0813-5
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