The iron–sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation
The iron–sulfur cluster helicase DDX11 promotes the generation of ssDNA and the phosphorylation of CHK1 at serine-345, possibly by unwinding replication-dependent DNA secondary structures. The iron–sulfur (FeS) cluster helicase DDX11 is associated with a human disorder termed Warsaw Breakage Syndrom...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Life Science Alliance LLC
2020-03-01
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| Seria: | Life Science Alliance |
| Dostęp online: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201900547 |
| Etykiety: |
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