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The iron–sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation

The iron–sulfur cluster helicase DDX11 promotes the generation of ssDNA and the phosphorylation of CHK1 at serine-345, possibly by unwinding replication-dependent DNA secondary structures. The iron–sulfur (FeS) cluster helicase DDX11 is associated with a human disorder termed Warsaw Breakage Syndrom...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Anna K Simon, Sandra Kummer, Sebastian Wild, Aleksandra Lezaja, Federico Teloni, Stanislaw K Jozwiakowski, Matthias Altmeyer, Kerstin Gari
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Life Science Alliance LLC 2020-03-01
Цуврал:Life Science Alliance
Онлайн хандалт:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201900547
Шошгууд: Шошго нэмэх
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