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Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson’s disease model

Abstract Background Cognitive decline occurs frequently in Parkinson’s disease (PD), which greatly decreases the quality of life of patients. However, the mechanisms remain to be investigated. Neuroinflammation mediated by overactivated microglia is a common pathological feature in multiple neurolog...

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Hlavní autoři: Dongdong Zhang, Sheng Li, Liyan Hou, Lu Jing, Zhengzheng Ruan, Bingjie Peng, Xiaomeng Zhang, Jau-Shyong Hong, Jie Zhao, Qingshan Wang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2021-01-01
Edice:Journal of Neuroinflammation
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On-line přístup:https://doi.org/10.1186/s12974-020-02065-z
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