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Targeting CD47-mediated cancer senescence, a novel strategy for cancer immunotherapy

A transmembrane protein that is extensively expressed, CD47 has an important role in the senescence of cancer cells. Therapy-induced senescence (TIS) by chemotherapy and radiotherapy restrains tumor proliferation yet drives immune evasion and treatment resistance, where CD47 acts as a core regulator...

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Bibliografiske detaljer
Principais autores: Bei Zhao, Chunlu Liao, Hailian Wang, Mingyi Chen, Jianing Yang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1815122/full
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