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Geniposide alleviates lipopolysaccharide-caused apoptosis of murine kidney podocytes by activating Ras/Raf/MEK/ERK-mediated cell autophagy

Proteinuria is one of the most important clinical features of nephrotic syndrome (NS). Injury of podocyte has been proved to contribute to the occurrence of proteinuria. This study explored the effects of geniposide (GEN) on lipopolysaccharide (LPS)-caused murine kidney podocyte MPC5 apoptosis and a...

Deskribapen osoa

Gorde:
Egile Nagusiak: Xia Li, Aijing Ma, Kun Liu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis Group 2019-12-01
Saila:Artificial Cells, Nanomedicine, and Biotechnology
Gaiak:
Nephrotic syndrome
podocytes
geniposide
cell apoptosis
cell autophagy
Ras/Raf/MEK/ERK pathway
Sarrera elektronikoa:https://www.tandfonline.com/doi/10.1080/21691401.2019.1601630
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