Low frequency deep brain stimulation of nucleus accumbens shell neuronal subpopulations attenuates cocaine seeking selectively in male rats

The present study examined the effect of deep brain stimulation (DBS) in the nucleus accumbens shell on cocaine seeking and neuronal plasticity in rats. Electrical DBS of the accumbens shell attenuated cocaine primed reinstatement across a range of frequencies as low as 12 Hz in male rats. Nucleus a...

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Auteurs principaux:	Sarah E. Swinford-Jackson, Matthew T. Rich, Phillip J. Huffman, Melissa C. Knouse, Arthur S. Thomas, Sharvari Mankame, Samantha J. Worobey, R. Christopher Pierce
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2023-12-01
Collection:	Addiction Neuroscience
Sujets:	Deep brain stimulation Nucleus accumbens Cocaine relapse Optogenetics LTP
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2772392523000767
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