Low frequency deep brain stimulation of nucleus accumbens shell neuronal subpopulations attenuates cocaine seeking selectively in male rats

The present study examined the effect of deep brain stimulation (DBS) in the nucleus accumbens shell on cocaine seeking and neuronal plasticity in rats. Electrical DBS of the accumbens shell attenuated cocaine primed reinstatement across a range of frequencies as low as 12 Hz in male rats. Nucleus a...

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Hlavní autoři:	Sarah E. Swinford-Jackson, Matthew T. Rich, Phillip J. Huffman, Melissa C. Knouse, Arthur S. Thomas, Sharvari Mankame, Samantha J. Worobey, R. Christopher Pierce
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-12-01
Edice:	Addiction Neuroscience
Témata:	Deep brain stimulation Nucleus accumbens Cocaine relapse Optogenetics LTP
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2772392523000767
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