Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD⁺-Glycohydrolase: Evidence for Extracellular Activity

ABSTRACT Group A Streptococcus (GAS) is a common human pathogen and the etiologic agent of a large number of diseases ranging from mild, self-limiting infections to invasive life-threatening conditions. Two prominent virulence factors of this bacterium are the genetically and functionally linked por...

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Detalhes bibliográficos

Principais autores:	Dóra Hancz, Elsa Westerlund, Benedicte Bastiat-Sempe, Onkar Sharma, Christine Valfridsson, Lena Meyer, John F. Love, Maghnus O’Seaghdha, Michael R. Wessels, Jenny J. Persson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2017-09-01
coleção:	mBio
Assuntos:	Streptococcus pyogenes host-pathogen interactions immune regulation innate immunity
Acesso em linha:	https://journals.asm.org/doi/10.1128/mBio.00756-17
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