Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors

Nuclear egress is an essential process in the replication of human cytomegalovirus (HCMV), as it enables the migration of newly formed viral capsids from the nucleus into the cytoplasm. Inhibition of the HCMV core nuclear egress complex (core NEC), composed of viral proteins pUL50 and pUL53, has bee...

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Detalhes bibliográficos

Principais autores:	Sewar Alkhashrom, Jintawee Kicuntod, Sigrun Häge, Johannes Schweininger, Yves A. Muller, Peter Lischka, Manfred Marschall, Jutta Eichler
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-03-01
coleção:	Viruses
Assuntos:	human cytomegalovirus nuclear egress complex (NEC) core NEC inhibitor antiviral activity small molecule inhibitor
Acesso em linha:	https://www.mdpi.com/1999-4915/13/3/471
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