CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
Abstract Aurora-A is an essential cell-cycle kinase with critical roles in mitotic entry and spindle dynamics. These functions require binding partners such as CEP192 and TPX2, which modulate both kinase activity and localisation of Aurora-A. Here we investigate the structure and role of the centros...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Nature
2024-09-01
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| Serie: | The EMBO Journal |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1038/s44318-024-00240-z |
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